Any plant that doesn’t display accusatory suffering when neglected is … Such formulations may be prepared as a liquid, solid or semisolid dosage form. Some of these compounds have exhibited moderate to good antiplasmoidal and antitrypanosomal effects in vitro. It’s a remarkable first aid medicine chest all in one. Scientifically Confirmed Effects: Stimulates the proliferation of fibroblasts (in-vitro study); Activates the production of high quality collagen (in-vitro study)Acts as collagen filler and lifting agent (in-vivo study)Reduces stretch marks and increases self esteem (in-vivo study)Provides fast results at a low concentration (in-vivo study)Repairs unsightly appearance of skin … I have now found that bulbine frutescens has important hydrating properties. The resulting extract can be formulated as is or it may be subjected to a suitable further processing and then incorporated into a suitable formulation form. Furthermore, the appearance of the skin is definitely improved. Experiments have shown that the Bulbine frutescens extract, formulated as a cream for example, leads to a definitely improved elasticity and a significantly improved strength of the skin, while at the same time greatly reducing the water loss of the subcutaneous tissue. CireNat Extract Bulbine Frutescens (INCI: Bulbine Frutescens Leaf Juice) relieves skin discomfort by providing anti-itch and redness reduction effects. In one embodiment, the juice is mixed with a quantity of hydrogen peroxide such that 0.5 to 20 g hydrogen peroxide, calculated as H2O2, is used per kilogram of the juice. Escherichia, Klebsiella and Enterobacter species (aerobic gram-negative rods, Enterobacteriaceae): inoculation 105 CFU/g. However any other stirrers may also be used. BotanicaTIMOLA® is derived from a plant with the botanical name Bulbine frutescens (L.) Willd.. PORTER WRIGHT MORRIS & ARTHUR, LLP (COLUMBUS, OH, US), Click for automatic bibliography Bull. Use of Bulbine frutescens Extract in Topical Candidiasis. Die Erfindung betrifft ein Bulbine-frutescens-Gel, das durch Verarbeitung der Blätter der Bulbine fructescens, Behandlung mit Wasserstoffperoxid, Beseitigung des restlichen Wasserstoffperoxids und Stabilisierung unter Verwendung eines geeigneten Stabilisierungsmittels in stabiler Form bereitgestellt wird. This may lead to an exacerbation of the condition of the wound and, if systemic infections occur, may lead to flu-like symptoms with fever for the patient. © 2004-2020 FreePatentsOnline.com. Bulbine frutescens enables the restoration of skin barrier function, … Since the first report about knipholone in representatives of the Asphodelaceae family, a number of other aryl-substituted chrysophanol derivatives have been described either as glycosides or aglycones. 32 1 (1987)). The extract was then incorporated into an antiperspirant formulation. The juice is expressed from a freshly picked leaf and applied to the area of skin affected. These vehicles and excipients include, for example, ion exchangers, emulsifiers, binders, suspension aids, stabilizers, bacteriostatic agents, antioxidants, lecithin, serum proteins, buffer substances, pH regulating agents, preservatives, water, salts and/or electrolytes, substances based on cellulose, and numerous other cosmetically or pharmaceutically acceptable additives. Such antimicrobial compositions may further include pharmaceutically-acceptable excipients and other additives (e.g., colorants, fragrances, preservatives, etc.) These results show advantages with regard to special microbial requirements. In the cosmetic field the extract may be used for body care, for example. Some embodiments described herein are pharmaceutical or cosmetic compositions comprising the extract. Peptococcus and Peptostreptococcus (anaerobic gram-positive cocci): inoculation 104 CFU/g. But in the near future it will become one of the best ground covers we have in central Florida. The fresh leaf of the plant produces a jellylike substance which is used in treating burns, blisters, rashes, insect bites, pimples, acne, cracked skin, etc. Six patients with breast cancer were asked to apply the extract as a preventive measure to the body area that was to be exposed to gamma rays. But in the near future it will become one of the best ground covers we have in central Florida. Such a combination disinfectant is even effective against Staphylococcus aureus including methicillin-resistant Staphylococcus aureus (MRSA) and clindamycin, erythromycin and ciprofloxacin-resistant Staphylococcus aureus (CEC-SA). Jun 26, 2014 - Bulbine frutescens is native to South Africa and is similar to Iceplant with its fleshy, succulent green leaves. 35, pp. Many South Africans plant Bulbine frutescens. Thus, for example, the Bulbine frutescens extract may be incorporated into a variety of antimicrobial compositions along with one or more additional antimicrobial agents, and optionally along with other therapeutic agents. The methyl group in position 3 may also be present in an oxidized form, either as the hydroxymethyl group, as an aldehyde or as an acid. Complete kill after 2 hours. We believe the skincare you use everyday should make a difference in your life, as well as in the lives of those who need it most. The ingredient also promotes skin recovery processes and increases skin hydration via natural lipid synthesis. Bulbine frutescens (L.) Willd., Asphodelaceae: Burn jelly plant: Slimy leaves: Topical: Rabe and Van Staden (1997), Van Wyk et al. USDA Zone? Be the first to review this product. Bulbine extract (Bulbine Frutescens Leaf Juice), from Swiss research, stimulates the creation of new cells, the skin becomes firmer and wrinkles will be filled in. Although this is true of plants in particular, they can also support the human body in fighting infections, as proposed by Yamada and Kiyohara (“Complement-activating polysaccharides from medicinal herbs”, Immunomodulatory Agents from Plants, 161-202 (1999), H. Wagner (ed. Share: Facebook; Pinterest Email; Bulbine Plant Features. Read Less. In 1987, the fundamental compound 1,8 dihydroxyanthraquinone (Danthron®) was taken off the market throughout the world because of the well-founded suspicion that this compound is carcinogenic for humans. The proven antimicrobial properties of the Bulbine frutescens extract make it possible to provide products with advantages with regard to special antimicrobial requirements. Bulbine Natalensis is an herb from Southern and South Eastern Africa that has traditionally been used as an aphrodisiac as well as some other beneficial properties. Prod. Our commitment to your skin starts with in-depth research. In addition to a wide variety of therapeutic uses, it has been found that the Bulbine frutescens extract may also be used for body care as well as other cosmetic uses. Conventional antiperspirant formulations to which the Bulbine frutescens extract has been added are especially effective. The Bulbine frutescens extract is used in the therapeutic or cosmetic fields and has an especially good effect on diseases of the skin and mucous membranes, in particular infections or inflammations such as fungal diseases, in prevention and/or curing injuries to the skin and mucous membranes, in particular burn wounds, as a disinfectant, as an agent to improve the immune defense, for body care, oral care… It forms a clump about 1 ft. high and 2-3 ft. wide and is cold hardy to Zone 8. Placebo-controlled experiments were conducted, showing that rinsing out the mouth twice a day with 10% aqueous solution of the Bulbine frutescens extract completely eliminates unwanted mouth odor. Bacteroides and Fusobacterium species (anaerobic gram-negative rods): inoculation 104 CFU/g. A definitely improved visual presentation of the skin has also been observed. This study further validates the use of the Bulbine leaf gels for the treatment of skin … Bulbine natalensis and Bulbine frutescens promote cutaneous wound healing J Ethnopharmacol. Bulbine is unusual and hard to find presently. Rabe and Van Staden (J. Ethnopharmacology 56, 81 (1997)) have investigated the in vitro effect of dried extracts from the leaves of Bulbine frutescens for their microbiological effect against Staphylococcus aureus, Staphylococcus epidermidis and Bacillus subtilis. This study aimed to explore the scientific value of these plants through investigating the in vivo biochemical effects of Bulbine natalensis and Bulbine frutescens on cutaneous … In pigs, Bulbine natalensis leaf gel extracts healed wounds faster and better than untreated wounds. The skin is amazingly self-sufficient. This material provides ‘smart collagen management’; stimulating proliferation of fibroblasts, activating production of high quality … Ethlop. The plant has a root stalk with numerous wiry roots; the leaves are 15 cm long and 4 to 8 mm thick, of a light green color and are fleshy and without hair. Experiments in Microbiological Investigation and Evaluation of the Bulbine frutescens Extract. However, the Bulbine frutescens extract unexpectedly strengthens the transdermal transport (even in nails), as demonstrated by tests with the Franz diffusion cell. Bulbine frutescens 'Orange' SKU. Therefore, one or more pharmaceutically or cosmetically acceptable preservatives may be added to the Bulbine frutescens extract. Botanica Natural Products produces and supplies indigenous plant extracts, such as Bulbine frutescens, and oils in a socially and environmentally sustainable manner for the cosmeceutic and nutraceutic industries. The Bulbine frutescens extract can therefore be used advantageously to prevent or treat burn wounds, such as those that occur during bombardment with gamma rays. For this purpose, after appropriate processing of the leaves, treatment with hydrogen peroxide, elimination of the remaining hydrogen peroxide and stabilization at a suitable pH using a suitable stabilizer, the extract was obtained as already described in detail. Other examples, features, aspects, embodiments, and advantages of the invention will become apparent to those skilled in the art from the following description, which is by way of illustration, one of the best modes contemplated for carrying out the invention. A kinetic provocation test was performed on various microorganisms using the Bulbine frutescens extract. Human perspiration is odorless immediately after secretion but the sterol esters present in perspiration are subject to microbial hydrolysis which forms not only short chain carboxylic acids (acetic acid, baldrianic acid, butyric acid and isobutyric acid) but also androstenes. BULBINE FRUTESCENS EXTRACT IN VITRO STUDY Test design: Double-blind, placebo-controlled, randomised, half-sided; Test subjects: 21 female subjects, Caucasian skin, 45 – 65 years (average 59). Substituted 1,8-dihydroxyanthraquinones have also been found in various species of aloe such as Aloe barbadensis, Aloe ferox (which also belong to the Asphodelaceae family) and species of rhubarb such as Rheum rhabarbarum and Rheum palmatum (Chinese rhubarb). Comparative experiments in which hydrogen peroxide (for example, 0.05 wt %, expressed as H2O2) was tested alone did not yield the antimicrobial properties provided by Bulbine frutescens extract enriched with hydrogen peroxide (for example, 0.05 wt % expressed as H2O2). Asphodelaceae) INTRODUCTION. The Bulbine frutescens extract may be used as described above, or it may be subjected to further processing. Rather, any dosage form or formulation which includes the extract (or a product processed further from it) as an active ingredient is contemplated. Africa's Skin Saviour. The yeast Candida albicans and related species are responsible for various types of candidiasis, for example, topical or vaginal candidiasis. CAUTION: GlyPro products used together may cause irritation. Pharm. The sap from the leaves has wonderful skin healing properties. These are readily water soluble but after aging of these extracts or excessive heating, hydrolysis may occur and the anthraquinones become insoluble in water. For example, the elasticity of the skin and the strength of the skin increases, while there is a long-lasting positive influence on the water balance of the skin as well as cell differentiation and cell proliferation. Read More It appears that these polypeptides mimic the effect of decorin and … This website uses cookies and other technologies to personalize content and to show you more personalized ads (for example, Google Ads and Facebook) on this and other websites, as well as provide you with social media features on this website (such as, Facebook, Twitter, LinkedIn). Medicinal uses GR1, 12, 20 Some 41 Bulbine species occur in South Africa and 6-7 are used medicinally; the leaf gel of most of these is used, the species possibly interchangeably, as an external application for the treatment of sores, wounds, skin rashes, cracked lips, eczema and ringworm; less often also to relieve sciatica. The formulation did not have any negative effects on the commensal microflora of the skin. Is presumably attributable mainly to the skin is definitely improved all trademarks are the property bulbine frutescens for skin respective... 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